Dysembryoplastic
Neuroepithelial Tumor (DNT, DNET)
(click on image to
magnify)
(from l. to
r. CT, CT(bone window), T1W MR w/Gd, PDW
MR)This is a slowly growing lesion of uncertain origin,
typically presenting in the first two decades with seizures. The bland
histologic appearance is often suggestive of a hamartoma or a cortical
dysplasia. These lesions almost invariably involve the cortex. Their indolent
slow rate of growth, and superficial location, allow them to produce a scalloped
erosion of the inner table of the skull. They are usually well-demarcated and,
like this example, occasionally wedge-shaped. The DNT only rarely shows contrast
enhancement. It is considered to be a surgically curable lesion. DNT may
also be associated with adjacent cortical
dysplasias.
[Differential
Dx includes ganglioglioma, oligodendroglioma, and pleomorphic
xanthoastrocytoma. However, those other neoplasms usually enhance with
contrast and are not wedge-shaped.]
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